Science News

Sunday, February 22, 2009

Gene Therapy may be the answer to HIV.

http://www.newscientist.com/article/mg20126964.400-gene-therapy-promises-oneshot-treatment-for-hiv.html

Over the years patients had to take these costly, daily Antiviral medicines to slow down the HIV virus and slow down the decline of their CD4 cells. Scientists know the HIV virus attacks cells by getting through a surface protein on the white blood cells and then replicating itself inside the hosts. There are many ways scientists are trying to tackle this problem.

One way is to extract CD4 cells and infect them with a virus that has a gene which prevents the surface protein from being developed. Without the surface protein the virus can't enter its host and replicate. Eventually these altered CD4 cells are sent back into the body and they reproduce immune CD4 cells which should eventually replace the infected CD4 cells.

A second way to attack the virus is by use of genetically altered stem cells that have a gene that cut up the virus when it gets into the cell before it can replicate. This process has some difficulties because it is competiting with the host white blood cells.

The Final way discussed in this article is apparently a multiviral attack in which viruses contain genes that stop the surface protein from being created and genes that cut up HIV viruses that enter the cell so they can't replicate.

If things go the way as these researches hope we might find a less costly, bothersome way to cure HIV. You won't have to take a bunch of pills everyday and possibly you could become immune to the virus completely.

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